Help! I Received a “Dilute Specimen” Drug Test Result!

I Received a Dilute Specimen Result – What Should I Do?

If you receive a negative dilute result from a drug test, you may choose to ask for another test.

A dilute result occurs when the donor has consumed too much water before the test, leading to a specimen that is less concentrated. To avoid this, instruct donors to limit their fluid intake before testing. Typically, an extra glass of water is all they need; if they drink too much liquid, they’re more likely end up with a diluted specimen.

A negative dilute result doesn’t necessarily mean the donor has tampered with the sample, but tampering cannot be entirely ruled out. Dilution can happen when too much fluid is added to the sample, or when the donor drinks large quantities of liquid before the test.

What is a Dilute Specimen?

A dilute specimen is a urine sample with:

• Creatinine levels greater than 5 mg/dL but less than 20 mg/dL, and

• Specific gravity below 1.0010.

These two criteria are routinely checked on every urine sample tested in the lab. If both are met, the specimen is classified as a "dilute specimen".

When a urine specimen is dilute, it’s possible that any drugs present in the donor’s system may not be detected.

How to Avoid a Negative Dilute Drug Test

To prevent a negative dilute result, follow these guidelines:

• Test first thing in the morning: The donor’s first urine of the day is typically more concentrated, making it ideal for the test.

• Avoid overconsumption of fluids: The donor should avoid drinking more than 16 oz. of liquid before the test. If testing cannot be done first thing in the morning, the donor should empty their bladder about 2 hours before the test and limit fluid intake during that time.

• Choose substantial fluids and meals: If fluids are consumed, they should be substantial, such as milk, smoothies, or tomato juice. The donor should also eat a protein-rich meal or snack (e.g., eggs, cheese, or meat) before testing.

Following these simple steps will help prevent dilute or abnormal urine results, ensuring the test results will be a valid indicator that the donor is drug-free.

Post written by our Drug Program Manager, Laura E.